Hypercapnic acidosis induces mitochondrial dysfunction and impairs the ability of mesenchymal stem cells to promote distal lung epithelial repair

Acute respiratory distress syndrome (ARDS) is a devastating disorder characterized by diffuse inflammation and edema formation. The main management strategy, low tidal volume ventilation, can be associated with the development of hypercapnic acidosis (HCA). Mesenchymal stem cells (MSCs) are a promis...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Fergie, Nicola, Todd, Naomi, McClements, Lana, McAuley, Danny, O’Kane, Cecilia, Krasnodembskaya, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436662/
https://ncbi.nlm.nih.gov/pubmed/30649987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802056R
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