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Engineered Cytochrome c-Catalyzed Lactone-Carbene B–H Insertion

Previous work has demonstrated that variants of a heme protein, Rhodothermus marinus cytochrome c (Rma cyt c), catalyze abiological carbene boron–hydrogen (B–H) bond insertion with high efficiency and selectivity. Here we investigated this carbon–boron bondforming chemistry with cyclic, lactone-base...

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Bibliografiske detaljer
Udgivet i:Synlett
Main Authors: Chen, Kai, Huang, Xiongyi, Zhang, Shuo-Qing, Zhou, Andrew Z., Kan, S. B. Jennifer, Hong, Xin, Arnold, Frances H.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436545/
https://ncbi.nlm.nih.gov/pubmed/30930550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0037-1611662
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