Gut Microbiota-Based Pharmacokinetics and the Antidepressant Mechanism of Paeoniflorin

Paeoniflorin, the main component of Xiaoyao Wan, presents low oral bioavailability and unclear antidepressant mechanism. To elucidate the potential reasons for the low bioavailability of paeoniflorin and explore its antidepressant mechanism from the perspective of the gut microbiota, here, a chronic...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Yu, Jin-Bo, Zhao, Zhen-Xiong, Peng, Ran, Pan, Li-Bin, Fu, Jie, Ma, Shu-Rong, Han, Pei, Cong, Lin, Zhang, Zheng-Wei, Sun, Li-Xin, Jiang, Jian-Dong, Wang, Yan
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435784/
https://ncbi.nlm.nih.gov/pubmed/30949054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00268
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