Gut Microbiota-Based Pharmacokinetics and the Antidepressant Mechanism of Paeoniflorin

Paeoniflorin, the main component of Xiaoyao Wan, presents low oral bioavailability and unclear antidepressant mechanism. To elucidate the potential reasons for the low bioavailability of paeoniflorin and explore its antidepressant mechanism from the perspective of the gut microbiota, here, a chronic...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Yu, Jin-Bo, Zhao, Zhen-Xiong, Peng, Ran, Pan, Li-Bin, Fu, Jie, Ma, Shu-Rong, Han, Pei, Cong, Lin, Zhang, Zheng-Wei, Sun, Li-Xin, Jiang, Jian-Dong, Wang, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435784/
https://ncbi.nlm.nih.gov/pubmed/30949054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00268
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