Lysosomal Pathways and Autophagy Distinctively Control Endothelial Cell Behavior to Affect Tumor Vasculature

Cancer cell-stromal cell crosstalk is orchestrated by a plethora of ligand-receptor interactions generating a tumor microenvironment (TME) which favors tumor growth. The high pro-angiogenic nature of the TME perpetuates the chaotic network of structurally immature, low pericyte-covered vessels chara...

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Foilsithe in:Front Oncol
Main Authors: Schaaf, Marco B., Houbaert, Diede, Meçe, Odeta, To, San Kit, Ganne, Maarten, Maes, Hannelore, Agostinis, Patrizia
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2019
Ábhair:
Oncology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435524/
https://ncbi.nlm.nih.gov/pubmed/30949450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00171
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