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How to teach an old dog new tricks: Autophagy-independent action of chloroquine on the tumor vasculature

Chloroquine (CQ) is exploited in clinical trials as an autophagy blocker to potentiate anticancer therapy, but it is unknown if it solely acts by inhibiting cancer cell-autonomous autophagy. Our recent study shows that besides blocking cancer cell growth, CQ also affects endothelial cells (ECs) and...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Maes, Hannelore, Kuchnio, Anna, Carmeliet, Peter, Agostinis, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502691/
https://ncbi.nlm.nih.gov/pubmed/25484095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.36259
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