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How to teach an old dog new tricks: Autophagy-independent action of chloroquine on the tumor vasculature

Chloroquine (CQ) is exploited in clinical trials as an autophagy blocker to potentiate anticancer therapy, but it is unknown if it solely acts by inhibiting cancer cell-autonomous autophagy. Our recent study shows that besides blocking cancer cell growth, CQ also affects endothelial cells (ECs) and...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Maes, Hannelore, Kuchnio, Anna, Carmeliet, Peter, Agostinis, Patrizia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502691/
https://ncbi.nlm.nih.gov/pubmed/25484095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.36259
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