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Hemodynamic and Neuronal Responses to Cocaine Differ in Awake versus Anesthetized Animals: Optical Brain Imaging Study

Cocaine is a highly addictive drug with complex pharmacological effects. Most preclinical imaging studies investigating the effects of cocaine in the brain have been performed under anesthesia, which confounds findings. To tackle this problem, we used optical imaging to compare the effects of cocain...

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Pubblicato in:Neuroimage
Autori principali: Park, Kicheon, Chen, Wei, Volkow, Nora D., Allen, Craig P., Pan, Yingtian, Du, Congwu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435283/
https://ncbi.nlm.nih.gov/pubmed/30513396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2018.11.062
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