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Enhanced neuronal and blunted hemodynamic reactivity to cocaine in the prefrontal cortex following extended cocaine access: optical imaging study in anesthetized rats

Cocaine addiction is associated with dysfunction of the prefrontal cortex (PFC), which facilitates relapse and compulsive drug taking. To assess if cocaine’s effects on both neuronal and vascular activity contribute to PFC dysfunction, we used optical coherence tomography (OCT) and multiwavelength l...

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Detalhes bibliográficos
Publicado no:Addict Biol
Main Authors: Allen, Craig P, Park, Kicheon, Li, Ang, Volkow, Nora D, Koob, George F, Pan, Yingtian, Hu, Xiu-Ti, Du, Congwu
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123312/
https://ncbi.nlm.nih.gov/pubmed/29504647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12615
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