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Enhanced neuronal and blunted hemodynamic reactivity to cocaine in the prefrontal cortex following extended cocaine access: optical imaging study in anesthetized rats

Cocaine addiction is associated with dysfunction of the prefrontal cortex (PFC), which facilitates relapse and compulsive drug taking. To assess if cocaine’s effects on both neuronal and vascular activity contribute to PFC dysfunction, we used optical coherence tomography (OCT) and multiwavelength l...

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Détails bibliographiques
Publié dans:Addict Biol
Auteurs principaux: Allen, Craig P, Park, Kicheon, Li, Ang, Volkow, Nora D, Koob, George F, Pan, Yingtian, Hu, Xiu-Ti, Du, Congwu
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123312/
https://ncbi.nlm.nih.gov/pubmed/29504647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12615
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