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Enhanced neuronal and blunted hemodynamic reactivity to cocaine in the prefrontal cortex following extended cocaine access: optical imaging study in anesthetized rats

Cocaine addiction is associated with dysfunction of the prefrontal cortex (PFC), which facilitates relapse and compulsive drug taking. To assess if cocaine’s effects on both neuronal and vascular activity contribute to PFC dysfunction, we used optical coherence tomography (OCT) and multiwavelength l...

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Dettagli Bibliografici
Pubblicato in:Addict Biol
Autori principali: Allen, Craig P, Park, Kicheon, Li, Ang, Volkow, Nora D, Koob, George F, Pan, Yingtian, Hu, Xiu-Ti, Du, Congwu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123312/
https://ncbi.nlm.nih.gov/pubmed/29504647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12615
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