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Extended Access to Cocaine Self-Administration Produces Long-Lasting Prefrontal Cortex-Dependent Working Memory Impairments

Humans with drug addiction exhibit compulsive drug-seeking associated with impairment of prefrontal cortex cognitive function. Whether prefrontal cortex dysfunction is a consequence of chronic drug exposure, or mediates the transition from drug use to drug dependence, is unknown. The current study i...

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Bibliografiske detaljer
Main Authors: George, Olivier, Mandyam, Chitra D, Wee, Sunmee, Koob, George F
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760333/
https://ncbi.nlm.nih.gov/pubmed/18033234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1301626
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