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Inhibition of kappa opioid receptors attenuated increased cocaine intake in rats with extended access to cocaine
OBJECTIVE: Previous studies demonstrated that the dynorphin/κ opioid system was up-regulated upon repeated cocaine self-administration. In the present study, we tested the hypothesis that increased cocaine self-administration with extended access was associated with increased activity of the κ opioi...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739447/ https://ncbi.nlm.nih.gov/pubmed/19484223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-009-1563-y |
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