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α(1)-Noradrenergic System Role in Increased Motivation for Cocaine Intake in Rats with Prolonged Access
In rodents, extended access to cocaine produces an escalation in cocaine self-administration that has face and construct validity for human compulsive drug intake. Here we report that rats with six-hour access (long access, LgA) to cocaine self-administration produced a higher breakpoint for cocaine...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2376122/ https://ncbi.nlm.nih.gov/pubmed/17920248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2007.08.003 |
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