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Cocaine-induced ischemia in prefrontal cortex is associated with escalation of cocaine intake in rodents
Cocaine-induced vasoconstriction reduces blood flow, which can jeopardize neuronal function and in the prefrontal cortex (PFC) it may contribute to compulsive cocaine intake. Here we used integrated optical imaging in a rat self-administration and a mouse non-contingent model, to investigate whether...
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| Udgivet i: | Mol Psychiatry |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6447479/ https://ncbi.nlm.nih.gov/pubmed/30283033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0261-8 |
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