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NGS based haplotype assembly using matrix completion

We apply matrix completion methods for haplotype assembly from NGS reads to develop the new HapSVT, HapNuc, and HapOPT algorithms. This is performed by applying a mathematical model to convert the reads to an incomplete matrix and estimating unknown components. This process is followed by quantizing...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Majidian, Sina, Kahaei, Mohammad Hossein
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435133/
https://ncbi.nlm.nih.gov/pubmed/30913270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214455
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