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NGS based haplotype assembly using matrix completion

We apply matrix completion methods for haplotype assembly from NGS reads to develop the new HapSVT, HapNuc, and HapOPT algorithms. This is performed by applying a mathematical model to convert the reads to an incomplete matrix and estimating unknown components. This process is followed by quantizing...

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Publicat a:PLoS One
Autors principals: Majidian, Sina, Kahaei, Mohammad Hossein
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435133/
https://ncbi.nlm.nih.gov/pubmed/30913270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214455
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