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NGS based haplotype assembly using matrix completion

We apply matrix completion methods for haplotype assembly from NGS reads to develop the new HapSVT, HapNuc, and HapOPT algorithms. This is performed by applying a mathematical model to convert the reads to an incomplete matrix and estimating unknown components. This process is followed by quantizing...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Majidian, Sina, Kahaei, Mohammad Hossein
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435133/
https://ncbi.nlm.nih.gov/pubmed/30913270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214455
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