Does reduced oxygen delivery cause lactic acidosis in falciparum malaria? An observational study

BACKGROUND: Lactic acidosis with an elevated lactate–pyruvate ratio suggesting anoxia is a common feature of severe falciparum malaria. High lactate levels are associated with parasitized erythrocyte sequestration in the microcirculation. To assess if there is an additional contribution to hyperlact...

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Publicado en:Malar J
Autores principales: Kingston, Hugh W., Ghose, Aniruddha, Rungpradubvong, Voravut, Herdman, M. Trent, Plewes, Katherine, Ishioka, Haruhiko, Leopold, Stije J., Maude, Richard J., Intharabut, Benjamas, Mohanty, Sanjib, Day, Nicholas P. J., White, Nicholas J., Hossain, Md Amir, Anstey, Nicholas M., Dondorp, Arjen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434797/
https://ncbi.nlm.nih.gov/pubmed/30909915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-019-2733-y
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