Does reduced oxygen delivery cause lactic acidosis in falciparum malaria? An observational study

BACKGROUND: Lactic acidosis with an elevated lactate–pyruvate ratio suggesting anoxia is a common feature of severe falciparum malaria. High lactate levels are associated with parasitized erythrocyte sequestration in the microcirculation. To assess if there is an additional contribution to hyperlact...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Kingston, Hugh W., Ghose, Aniruddha, Rungpradubvong, Voravut, Herdman, M. Trent, Plewes, Katherine, Ishioka, Haruhiko, Leopold, Stije J., Maude, Richard J., Intharabut, Benjamas, Mohanty, Sanjib, Day, Nicholas P. J., White, Nicholas J., Hossain, Md Amir, Anstey, Nicholas M., Dondorp, Arjen M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434797/
https://ncbi.nlm.nih.gov/pubmed/30909915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-019-2733-y
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