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Efficacy and safety of sonic hedgehog pathway inhibitors in cancer

The hedgehog pathway, for which sonic hedgehog (Shh) is the most prominent ligand, is highly conserved and is tightly associated with embryonic development in a number of species. This pathway is also tightly associated with development of several types of cancer, including basal cell carcinoma and...

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Bibliografische gegevens
Gepubliceerd in:Drug Saf
Hoofdauteurs: Carpenter, Richard L, Ray, Haimanti
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434684/
https://ncbi.nlm.nih.gov/pubmed/30649745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40264-018-0777-5
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