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Efficacy and safety of sonic hedgehog pathway inhibitors in cancer

The hedgehog pathway, for which sonic hedgehog (Shh) is the most prominent ligand, is highly conserved and is tightly associated with embryonic development in a number of species. This pathway is also tightly associated with development of several types of cancer, including basal cell carcinoma and...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Drug Saf
Hauptverfasser: Carpenter, Richard L, Ray, Haimanti
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434684/
https://ncbi.nlm.nih.gov/pubmed/30649745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40264-018-0777-5
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