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Efficacy and safety of sonic hedgehog pathway inhibitors in cancer

The hedgehog pathway, for which sonic hedgehog (Shh) is the most prominent ligand, is highly conserved and is tightly associated with embryonic development in a number of species. This pathway is also tightly associated with development of several types of cancer, including basal cell carcinoma and...

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Detalhes bibliográficos
Publicado no:Drug Saf
Main Authors: Carpenter, Richard L, Ray, Haimanti
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434684/
https://ncbi.nlm.nih.gov/pubmed/30649745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40264-018-0777-5
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