Single Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression

Chromosomal aneuploidy is a defining feature of carcinomas and results in tumor-entity specific genomic imbalances. For instance, most sporadic colorectal carcinomas carry extra copies of chromosome 7, an aneuploidy that emerges already in premalignant adenomas, and is maintained throughout tumor pr...

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Pubblicato in:Neoplasia
Autori principali: Braun, Rüdiger, Ronquist, Scott, Wangsa, Darawalee, Chen, Haiming, Anthuber, Lena, Gemoll, Timo, Wangsa, Danny, Koparde, Vishal, Hunn, Cynthia, Habermann, Jens K., Heselmeyer-Haddad, Kerstin, Rajapakse, Indika, Ried, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press 2019
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Original article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434407/
https://ncbi.nlm.nih.gov/pubmed/30909073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.02.003
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