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Chromosome Conformation of Human Fibroblasts Grown in 3-Dimensional Spheroids
In the study of interphase chromosome organization, genome-wide chromosome conformation capture (Hi-C) maps are often generated using 2-dimensional (2D) monolayer cultures. These 2D cells have morphological deviations from cells that exist in 3-dimensional (3D) tissues in vivo, and may not maintain...
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| Publié dans: | Nucleus |
|---|---|
| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615318/ https://ncbi.nlm.nih.gov/pubmed/25738643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2014.1003745 |
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