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Notch Inhibition Promotes Differentiation of Liver Progenitor Cells into Hepatocytes via sox9b Repression in Zebrafish

Liver regeneration after most forms of injury is mediated through the proliferation of hepatocytes. However, when hepatocyte proliferation is impaired, such as during chronic liver disease, liver progenitor cells (LPCs) arising from the biliary epithelial cell (BEC) compartment can give rise to hepa...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Russell, Jacquelyn O., Ko, Sungjin, Monga, Satdarshan P., Shin, Donghun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434270/
https://ncbi.nlm.nih.gov/pubmed/30992706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8451282
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