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Attenuating the EGFR-ERK-SOX9 axis promotes liver progenitor cell-mediated liver regeneration in zebrafish

The liver is a highly regenerative organ, but its regenerative capacity is compromised in severe liver injury settings. In chronic liver diseases, the number of liver progenitor cells (LPCs) correlates proportionally to disease severity, implying that their inefficient differentiation into hepatocyt...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: So, Juhoon, Kim, Minwook, Lee, Seung-Hoon, Ko, Sungjin, Lee, Daniel A., Park, Hyewon, Azuma, Mizuki, Parsons, Michael J., Prober, David, Shin, Donghun
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769917/
https://ncbi.nlm.nih.gov/pubmed/32602149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31437
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