Attenuating the EGFR-ERK-SOX9 axis promotes liver progenitor cell-mediated liver regeneration in zebrafish

The liver is a highly regenerative organ, but its regenerative capacity is compromised in severe liver injury settings. In chronic liver diseases, the number of liver progenitor cells (LPCs) correlates proportionally to disease severity, implying that their inefficient differentiation into hepatocyt...

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Gepubliceerd in:Hepatology
Hoofdauteurs: So, Juhoon, Kim, Minwook, Lee, Seung-Hoon, Ko, Sungjin, Lee, Daniel A., Park, Hyewon, Azuma, Mizuki, Parsons, Michael J., Prober, David, Shin, Donghun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769917/
https://ncbi.nlm.nih.gov/pubmed/32602149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31437
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