Attenuating the EGFR-ERK-SOX9 axis promotes liver progenitor cell-mediated liver regeneration in zebrafish

The liver is a highly regenerative organ, but its regenerative capacity is compromised in severe liver injury settings. In chronic liver diseases, the number of liver progenitor cells (LPCs) correlates proportionally to disease severity, implying that their inefficient differentiation into hepatocyt...

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Bibliographic Details
Published in:Hepatology
Main Authors: So, Juhoon, Kim, Minwook, Lee, Seung-Hoon, Ko, Sungjin, Lee, Daniel A., Park, Hyewon, Azuma, Mizuki, Parsons, Michael J., Prober, David, Shin, Donghun
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769917/
https://ncbi.nlm.nih.gov/pubmed/32602149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31437
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