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Artificial Selection for Pathogenicity Mutations in Staphylococcus aureus Identifies Novel Factors Relevant to Chronic Infection

Adaptation of Staphylococcus aureus to host microenvironments during chronic infection involves spontaneous mutations, yet changes underlying adaptive phenotypes remain incompletely explored. Here, we employed artificial selection and whole-genome sequencing to better characterize spontaneous chromo...

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書誌詳細
出版年:Infect Immun
主要な著者: McLean, Kathryn, Holmes, Elizabeth A., Penewit, Kelsi, Lee, Duankun K., Hardy, Samantha R., Ren, Mingxin, Krist, Maxwell P., Huang, Kevin, Waalkes, Adam, Salipante, Stephen J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434136/
https://ncbi.nlm.nih.gov/pubmed/30642903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00884-18
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