Artificial Selection for Pathogenicity Mutations in Staphylococcus aureus Identifies Novel Factors Relevant to Chronic Infection

Adaptation of Staphylococcus aureus to host microenvironments during chronic infection involves spontaneous mutations, yet changes underlying adaptive phenotypes remain incompletely explored. Here, we employed artificial selection and whole-genome sequencing to better characterize spontaneous chromo...

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Detaylı Bibliyografya
Yayımlandı:Infect Immun
Asıl Yazarlar: McLean, Kathryn, Holmes, Elizabeth A., Penewit, Kelsi, Lee, Duankun K., Hardy, Samantha R., Ren, Mingxin, Krist, Maxwell P., Huang, Kevin, Waalkes, Adam, Salipante, Stephen J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2019
Konular:
Bacterial Infections
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434136/
https://ncbi.nlm.nih.gov/pubmed/30642903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00884-18
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