Artificial Selection for Pathogenicity Mutations in Staphylococcus aureus Identifies Novel Factors Relevant to Chronic Infection

Adaptation of Staphylococcus aureus to host microenvironments during chronic infection involves spontaneous mutations, yet changes underlying adaptive phenotypes remain incompletely explored. Here, we employed artificial selection and whole-genome sequencing to better characterize spontaneous chromo...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: McLean, Kathryn, Holmes, Elizabeth A., Penewit, Kelsi, Lee, Duankun K., Hardy, Samantha R., Ren, Mingxin, Krist, Maxwell P., Huang, Kevin, Waalkes, Adam, Salipante, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434136/
https://ncbi.nlm.nih.gov/pubmed/30642903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00884-18
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