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A Glucuronoxylomannan Epitope Exhibits Serotype-Specific Accessibility and Redistributes towards the Capsule Surface during Titanization of the Fungal Pathogen Cryptococcus neoformans

Disseminated infections with the fungal species Cryptococcus neoformans or, less frequently, Cryptococcus gattii are an important cause of mortality in immunocompromised individuals. Central to the virulence of both species is an elaborate polysaccharide capsule that consists predominantly of glucur...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Probert, Mark, Zhou, Xin, Goodall, Margaret, Johnston, Simon A., Bielska, Ewa, Ballou, Elizabeth R., May, Robin C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434129/
https://ncbi.nlm.nih.gov/pubmed/30670549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00731-18
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