A Glucuronoxylomannan Epitope Exhibits Serotype-Specific Accessibility and Redistributes towards the Capsule Surface during Titanization of the Fungal Pathogen Cryptococcus neoformans

Disseminated infections with the fungal species Cryptococcus neoformans or, less frequently, Cryptococcus gattii are an important cause of mortality in immunocompromised individuals. Central to the virulence of both species is an elaborate polysaccharide capsule that consists predominantly of glucur...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Probert, Mark, Zhou, Xin, Goodall, Margaret, Johnston, Simon A., Bielska, Ewa, Ballou, Elizabeth R., May, Robin C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434129/
https://ncbi.nlm.nih.gov/pubmed/30670549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00731-18
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