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Contributions of TolC Orthologs to Francisella tularensis Schu S4 Multidrug Resistance, Modulation of Host Cell Responses, and Virulence

Francisella tularensis is a Gram-negative, facultative intracellular pathogen and the causative agent of tularemia. Previous studies with the attenuated live vaccine strain (LVS) identified a role for the outer membrane protein TolC in modulation of host cell responses during infection and virulence...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Kopping, Erik J., Doyle, Christopher R., Sampath, Vinaya, Thanassi, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434128/
https://ncbi.nlm.nih.gov/pubmed/30670554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00823-18
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