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TolC-Dependent Modulation of Host Cell Death by the Francisella tularensis Live Vaccine Strain

Francisella tularensis is a facultative intracellular, Gram-negative pathogen and the causative agent of tularemia. We previously identified TolC as a virulence factor of the F. tularensis live vaccine strain (LVS) and demonstrated that a ΔtolC mutant exhibits increased cytotoxicity toward host cell...

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Autores principales: Doyle, Christopher R., Pan, Ji-An, Mena, Patricio, Zong, Wei-Xing, Thanassi, David G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993420/
https://ncbi.nlm.nih.gov/pubmed/24614652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00044-14
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