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Deletion of TolC orthologs in Francisella tularensis identifies roles in multidrug resistance and virulence

The Gram-negative bacterium Francisella tularensis is the causative agent of tularemia. Interest in this zoonotic pathogen has increased due to its classification as a category A agent of bioterrorism, but little is known about the molecular mechanisms underlying its virulence, and especially what s...

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Main Authors: Gil, Horacio, Platz, Gabrielle J., Forestal, Colin A., Monfett, Michael, Bakshi, Chandra Shekhar, Sellati, Timothy J., Furie, Martha B., Benach, Jorge L., Thanassi, David G.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1568944/
https://ncbi.nlm.nih.gov/pubmed/16908853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602582103
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