Kinetic and Cross-Sectional Studies on the Genesis of Hypoargininemia in Severe Pediatric Plasmodium falciparum Malaria

The low bioavailability of nitric oxide (NO) and its precursor, arginine, contributes to the microvascular pathophysiology of severe falciparum malaria. To better characterize the mechanisms underlying hypoargininemia in severe malaria, we measured the plasma concentrations of amino acids involved i...

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Gepubliceerd in:Infect Immun
Hoofdauteurs: Rubach, Matthew P., Zhang, Haoyue, Florence, Salvatore M., Mukemba, Jackson P., Kalingonji, Ayam R., Anstey, Nicholas M., Yeo, Tsin W., Lopansri, Bert K., Thompson, J. Will, Mwaikambo, Esther D., Young, Sarah, Millington, David S., Weinberg, J. Brice, Granger, Donald L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2019
Onderwerpen:
Fungal and Parasitic Infections
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434111/
https://ncbi.nlm.nih.gov/pubmed/30718287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00655-18
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