Skeletal muscle Nur77 and NOR1 insulin responsiveness is blunted in obesity and type 2 diabetes but improved after exercise training

Obesity and type 2 diabetes (T2DM) are characterized by a blunted metabolic response to insulin, and strongly manifests in skeletal muscle insulin resistance. The orphan nuclear receptors, Nur77 and NOR1, regulate insulin‐stimulated nutrient metabolism where Nur77 and NOR1 gene expression is increas...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Physiol Rep
Hlavní autoři: Mey, Jacob T., Solomon, Thomas P. J., Kirwan, John P., Haus, Jacob M.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434071/
https://ncbi.nlm.nih.gov/pubmed/30912283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14042
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky