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Dicarbonyl Stress and Glyoxalase-1 in Skeletal Muscle: Implications for Insulin Resistance and Type 2 Diabetes

Glyoxalase-1 (GLO1) is a ubiquitously expressed cytosolic protein which plays a role in the natural maintenance of cellular health and is abundantly expressed in human skeletal muscle. A consequence of reduced GLO1 protein expression is cellular dicarbonyl stress, which is elevated in obesity, insul...

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Vydáno v:Front Cardiovasc Med
Hlavní autoři: Mey, Jacob T., Haus, Jacob M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139330/
https://ncbi.nlm.nih.gov/pubmed/30250846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2018.00117
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