Skeletal muscle Nur77 and NOR1 insulin responsiveness is blunted in obesity and type 2 diabetes but improved after exercise training

Obesity and type 2 diabetes (T2DM) are characterized by a blunted metabolic response to insulin, and strongly manifests in skeletal muscle insulin resistance. The orphan nuclear receptors, Nur77 and NOR1, regulate insulin‐stimulated nutrient metabolism where Nur77 and NOR1 gene expression is increas...

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Bibliografiska uppgifter
I publikationen:Physiol Rep
Huvudupphovsmän: Mey, Jacob T., Solomon, Thomas P. J., Kirwan, John P., Haus, Jacob M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2019
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434071/
https://ncbi.nlm.nih.gov/pubmed/30912283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14042
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