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Dicarbonyl stress and glyoxalase enzyme system regulation in human skeletal muscle
Skeletal muscle insulin resistance is a hallmark of Type 2 diabetes (T2DM) and may be exacerbated by protein modifications by methylglyoxal (MG), known as dicarbonyl stress. The glyoxalase enzyme system composed of glyoxalase 1/2 (GLO1/GLO2) is the natural defense against dicarbonyl stress, yet its...
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| Pubblicato in: | Am J Physiol Regul Integr Comp Physiol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5867671/ https://ncbi.nlm.nih.gov/pubmed/29046313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00159.2017 |
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