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Enhancing folic acid metabolism suppresses defects associated with loss of Drosophila mitofusin
Mutations in the mitochondrial GTPase mitofusin 2 (MFN2) cause Charcot-Marie-Tooth disease type 2 (CMT2A), a form of peripheral neuropathy that compromises axonal function. Mitofusins promote mitochondrial fusion and regulate mitochondrial dynamics. They are also reported to be involved in forming c...
Shranjeno v:
| izdano v: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6433915/ https://ncbi.nlm.nih.gov/pubmed/30911005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1496-2 |
| Oznake: |
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