Conditional Inactivation of Pen-2 in the Developing Neocortex Leads to Rapid Switch of Apical Progenitors to Basal Progenitors

The transition of apical progenitors (APs) to basal progenitors (BPs) is an important neurogenic process during cortical expansion. Presenilin enhancer 2 (Pen-2, also named as Psenen) is a key subunit of γ-secretase and has been implicated in neurodevelopmental disease. However, it remains unknown h...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Cheng, Shanshan, Liu, Tingting, Hu, Yimin, Xia, Yingqian, Hou, Jinxing, Huang, Chaoli, Zou, Xiaochuan, Liang, Juan, Stone Shi, Yun, Zheng, Yuanlin, Lu, Jun, Chen, Guiquan
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433762/
https://ncbi.nlm.nih.gov/pubmed/30692224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2523-18.2019
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