Conditional Inactivation of Pen-2 in the Developing Neocortex Leads to Rapid Switch of Apical Progenitors to Basal Progenitors

The transition of apical progenitors (APs) to basal progenitors (BPs) is an important neurogenic process during cortical expansion. Presenilin enhancer 2 (Pen-2, also named as Psenen) is a key subunit of γ-secretase and has been implicated in neurodevelopmental disease. However, it remains unknown h...

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Udgivet i:J Neurosci
Main Authors: Cheng, Shanshan, Liu, Tingting, Hu, Yimin, Xia, Yingqian, Hou, Jinxing, Huang, Chaoli, Zou, Xiaochuan, Liang, Juan, Stone Shi, Yun, Zheng, Yuanlin, Lu, Jun, Chen, Guiquan
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433762/
https://ncbi.nlm.nih.gov/pubmed/30692224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2523-18.2019
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