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Allosteric Modulators of Sigma-1 Receptor: A Review
Allosteric modulators of sigma-1 receptor (Sig1R) are described as compounds that can increase the activity of some Sig1R ligands that compete with (+)-pentazocine, one of the classic prototypical ligands that binds to the orthosteric Sig1R binding site. Sig1R is an endoplasmic reticulum membrane pr...
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| Published in: | Front Pharmacol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Frontiers Media S.A.
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6433746/ https://ncbi.nlm.nih.gov/pubmed/30941035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00223 |
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