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Allosteric Modulators of Sigma-1 Receptor: A Review

Allosteric modulators of sigma-1 receptor (Sig1R) are described as compounds that can increase the activity of some Sig1R ligands that compete with (+)-pentazocine, one of the classic prototypical ligands that binds to the orthosteric Sig1R binding site. Sig1R is an endoplasmic reticulum membrane pr...

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Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Vavers, Edijs, Zvejniece, Liga, Maurice, Tangui, Dambrova, Maija
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433746/
https://ncbi.nlm.nih.gov/pubmed/30941035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00223
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