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Delivery of mitoxantrone using a plant virus-based nanoparticle for the treatment of glioblastomas

Mitoxatrone (MTO), an antineoplastic chemotherapeutic, has potent activity against the most common and agressive type of primary brain tumor, glioblastoma multiforme (GBM). However, its poor penetration through the blood brain barrier, and cardiotoxic side effects from systemic delivery limit its ef...

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Podrobná bibliografie
Vydáno v:J Mater Chem B
Hlavní autoři: Lam, Patricia, Lin, Richard, Steinmetz, Nicole F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433411/
https://ncbi.nlm.nih.gov/pubmed/30923616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C8TB01191E
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