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Delivery of mitoxantrone using a plant virus-based nanoparticle for the treatment of glioblastomas

Mitoxatrone (MTO), an antineoplastic chemotherapeutic, has potent activity against the most common and agressive type of primary brain tumor, glioblastoma multiforme (GBM). However, its poor penetration through the blood brain barrier, and cardiotoxic side effects from systemic delivery limit its ef...

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Dettagli Bibliografici
Pubblicato in:J Mater Chem B
Autori principali: Lam, Patricia, Lin, Richard, Steinmetz, Nicole F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433411/
https://ncbi.nlm.nih.gov/pubmed/30923616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C8TB01191E
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