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Delivery of mitoxantrone using a plant virus-based nanoparticle for the treatment of glioblastomas

Mitoxatrone (MTO), an antineoplastic chemotherapeutic, has potent activity against the most common and agressive type of primary brain tumor, glioblastoma multiforme (GBM). However, its poor penetration through the blood brain barrier, and cardiotoxic side effects from systemic delivery limit its ef...

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Detalhes bibliográficos
Publicado no:J Mater Chem B
Main Authors: Lam, Patricia, Lin, Richard, Steinmetz, Nicole F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433411/
https://ncbi.nlm.nih.gov/pubmed/30923616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C8TB01191E
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