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METHYLENE BLUE DOES NOT BYPASS COMPLEX III ANTIMYCIN BLOCK IN MOUSE BRAIN MITOCHONDRIA
Methylene blue (MB) is a promising prodrug to treat mitochondrial dysfunctions that is currently being used in clinical trials for Alzheimer’s disease. MB can penetrate the blood brain barrier, accumulating in brain mitochondria where it acts as a redox mediator in the electron transfer chain (ETC)....
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| Publicado no: | FEBS Lett |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6433145/ https://ncbi.nlm.nih.gov/pubmed/30734287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13332 |
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