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METHYLENE BLUE DOES NOT BYPASS COMPLEX III ANTIMYCIN BLOCK IN MOUSE BRAIN MITOCHONDRIA
Methylene blue (MB) is a promising prodrug to treat mitochondrial dysfunctions that is currently being used in clinical trials for Alzheimer’s disease. MB can penetrate the blood brain barrier, accumulating in brain mitochondria where it acts as a redox mediator in the electron transfer chain (ETC)....
Gardado en:
| Publicado en: | FEBS Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6433145/ https://ncbi.nlm.nih.gov/pubmed/30734287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13332 |
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