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Low Plasma ADAMTS13 Activity is Associated with Coagulopathy, Endothelial Cell Damage and Mortality after Severe Pediatric Trauma

Decrease of plasma activity of ADAMTS13, a metalloenzyme that cleaves von Willebrand factor (VWF) and prevents adhesion and aggregation of platelets, has been reported early after onset of systemic inflammation resulting from infections and after severe trauma. Here, we determined whether trauma-ind...

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Détails bibliographiques
Publié dans:Thromb Haemost
Auteurs principaux: Russell, Robert T, McDaniel, Jenny K., Cao, Wenjing, Shroyer, Michelle, Wagener, Brant M., Zheng, X. Long, Pittet, Jean-François
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433136/
https://ncbi.nlm.nih.gov/pubmed/29618154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0038-1636528
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