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Low Plasma ADAMTS13 Activity is Associated with Coagulopathy, Endothelial Cell Damage and Mortality after Severe Pediatric Trauma

Decrease of plasma activity of ADAMTS13, a metalloenzyme that cleaves von Willebrand factor (VWF) and prevents adhesion and aggregation of platelets, has been reported early after onset of systemic inflammation resulting from infections and after severe trauma. Here, we determined whether trauma-ind...

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Bibliografische gegevens
Gepubliceerd in:Thromb Haemost
Hoofdauteurs: Russell, Robert T, McDaniel, Jenny K., Cao, Wenjing, Shroyer, Michelle, Wagener, Brant M., Zheng, X. Long, Pittet, Jean-François
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433136/
https://ncbi.nlm.nih.gov/pubmed/29618154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0038-1636528
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