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Low Plasma ADAMTS13 Activity is Associated with Coagulopathy, Endothelial Cell Damage and Mortality after Severe Pediatric Trauma

Decrease of plasma activity of ADAMTS13, a metalloenzyme that cleaves von Willebrand factor (VWF) and prevents adhesion and aggregation of platelets, has been reported early after onset of systemic inflammation resulting from infections and after severe trauma. Here, we determined whether trauma-ind...

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Dettagli Bibliografici
Pubblicato in:Thromb Haemost
Autori principali: Russell, Robert T, McDaniel, Jenny K., Cao, Wenjing, Shroyer, Michelle, Wagener, Brant M., Zheng, X. Long, Pittet, Jean-François
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433136/
https://ncbi.nlm.nih.gov/pubmed/29618154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0038-1636528
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