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The ubiquitin-like modifier FAT10 stimulates the activity of deubiquitylating enzyme OTUB1

The deubiquitylation of target proteins is mediated by deubiquitylating enzymes (DUB) such as OTUB1, which plays an important role in immune response, cell cycle progression, and DNA repair. Within these processes, OTUB1 reduces the ubiquitylation of target proteins in two distinct ways, either by u...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Bialas, Johanna, Boehm, Annika N., Catone, Nicola, Aichem, Annette, Groettrup, Marcus
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433071/
https://ncbi.nlm.nih.gov/pubmed/30718280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005406
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