Overexpression of the C-domain of angiotensin-converting enzyme reduces melanoma growth by stimulating M1 macrophage polarization

Angiotensin-converting enzyme (ACE) can hydrolyze many peptides and plays a central role in controlling blood pressure. Moreover, ACE overexpression in monocytes and macrophages increases resistance of mice to tumor growth. ACE is composed of two independent catalytic domains. Here, to investigate t...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Khan, Zakir, Cao, Duo-Yao, Giani, Jorge F., Bernstein, Ellen A., Veiras, Luciana C., Fuchs, Sebastien, Wang, Yizhou, Peng, Zhenzi, Kalkum, Markus, Liu, George Y., Bernstein, Kenneth E.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2019
主題:
Protein Structure and Folding
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433053/
https://ncbi.nlm.nih.gov/pubmed/30670595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006275
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