Overexpression of the C-domain of angiotensin-converting enzyme reduces melanoma growth by stimulating M1 macrophage polarization

Angiotensin-converting enzyme (ACE) can hydrolyze many peptides and plays a central role in controlling blood pressure. Moreover, ACE overexpression in monocytes and macrophages increases resistance of mice to tumor growth. ACE is composed of two independent catalytic domains. Here, to investigate t...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Khan, Zakir, Cao, Duo-Yao, Giani, Jorge F., Bernstein, Ellen A., Veiras, Luciana C., Fuchs, Sebastien, Wang, Yizhou, Peng, Zhenzi, Kalkum, Markus, Liu, George Y., Bernstein, Kenneth E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433053/
https://ncbi.nlm.nih.gov/pubmed/30670595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006275
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker