Reduced Susceptibility to Neuraminidase Inhibitors in Influenza B Isolate, Canada

We identified an influenza B isolate harboring a Gly407Ser neuraminidase substitution in an immunocompromised patient in Canada before antiviral therapy. This mutation mediated reduced susceptibility to oseltamivir, zanamivir, and peramivir, most likely by preventing interaction with the catalytic A...

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Bibliographic Details
Published in:Emerg Infect Dis
Main Authors: Abed, Yacine, Fage, Clément, Lagüe, Patrick, Carbonneau, Julie, Papenburg, Jesse, Vinh, Donald C., Boivin, Guy
Format: Artigo
Language:Inglês
Published: Centers for Disease Control and Prevention 2019
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Research Letter
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433030/
https://ncbi.nlm.nih.gov/pubmed/30882323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid2504.181554
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